Prions arise when the cellular prion protein (PrP(C)) undergoes a self-propagating conformational change; the resulting infectious conformer is designated PrP(Sc).Frequently, PrP(Sc) is protease-resistant but protease-sensitive (s) prions have been isolated in humans and other animals.We report here that protease-sensitive, synthetic prions were ge
The article is devoted to solving the problems of the development of a cyclical economy in the conditions of globalization, since the further development of society while maintaining the current growth rates of production and consumption with increasing population can lead to a global catastrophe.The traditional development model is based on intens
Abstract Background Physical activity (PA) counselling is an effective approach to promote PA in primary health care (PHC).Barriers to PA counselling in PHC include time constraints, lack of knowledge and skills of providers, and systemic barriers.Using electronic health (eHealth) has the potential to promote PA.This scoping review aimed to identif
Over 1 million Americans are currently living with T1D and improvements in diabetes management have increased the number of adults with T1D living into later decades of life.This growing population of older adults with diabetes is more susceptible to aging comorbidities, including both vascular disease and osteoporosis.Indeed, adults with T1D have